neurosciencestuff:

Scientists Find Antibody that Transforms Bone Marrow Stem Cells Directly into Brain Cells

In a serendipitous discovery, scientists at The Scripps Research Institute (TSRI) have found a way to turn bone marrow stem cells directly into brain cells.

Current techniques for turning patients’ marrow cells into cells of some other desired type are relatively cumbersome, risky and effectively confined to the lab dish. The new finding points to the possibility of simpler and safer techniques. Cell therapies derived from patients’ own cells are widely expected to be useful in treating spinal cord injuries, strokes and other conditions throughout the body, with little or no risk of immune rejection.

“These results highlight the potential of antibodies as versatile manipulators of cellular functions,” said Richard A. Lerner, the Lita Annenberg Hazen Professor of Immunochemistry and institute professor in the Department of Cell and Molecular Biology at TSRI, and principal investigator for the new study. “This is a far cry from the way antibodies used to be thought of—as molecules that were selected simply for binding and not function.”

The researchers discovered the method, reported in the online Early Edition of the Proceedings of the National Academy of Sciences the week of April 22, 2013, while looking for lab-grown antibodies that can activate a growth-stimulating receptor on marrow cells. One antibody turned out to activate the receptor in a way that induces marrow stem cells—which normally develop into white blood cells—to become neural progenitor cells, a type of almost-mature brain cell.

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(via positive-press-daily)

timgspears:

Window Socket - Kyuho Song & Boa Oh

So this is an absolutley brilliant idea! Just attach the plug on to a window and it will harness solar energy. A small converter will convert it into electricity which can be freely used as a plug when you are in the car, on a plane or outside.

Love this design and I really think it has a great potential.

(via bankston)

(Source: qualed, via knowwhereishere)

darkarfs:

Boards of Canada, I like that you’re playing these games with my heart.

First the psychotic, sparsely and clandestinely released 12”s, and now a 90 sceond bump on Cartoon Network. 

Genuinely curious as to where they go next.

(Source: inestabledrugsandshits, via knowwhereishere)

jonathankroell:

_skizze
_sketch 

f-l-e-u-r-d-e-l-y-s:

biology fluorescence microscopy

source; natureofnature

1. This image depicts neural stem cells that were genetically modified with an engineered form of HIV. Visualized in green is a transgenic protein introduced by HIV; red is a stem cell stain, and blue depicts neuronal progeny.
2.  Cross-Section Tissue of Marram Grass Leaf
3. Image shows adult human fibroblast cells with intracellular proteins involved in adhesion of these cells to an extracellular matrix. Magenta represents actin stress fibers in a cell and green staining represents a focal adhesion protein vinculin, which together contribute to how strongly these cells adhere to a matrix surface. Blue is the nucleus of a cell.
4. Clematis vitalba
5. Human ovarian cancer cells stained for DNA (red) and microtubules (green).
6. Chicken embryo vascular system
7. Confocal micrograph showing the expression of different fluorescent proteins in the stem of a thale cress seedling (Arabidopsis thaliana).
8. Widefield image of a pilidium larvae of the Nemertean ribbon worm, Cerebratulus lacteus,
9. Acetabularia - gigantic single cell algae.

10. Confocal image of squid, Loligo pealei, embryo stained for for F-actin (green; phalloidin), Acetylated tubulin (red), anti-HRP (yellow), and DAPI (blue; nuclei)

(via molecularlifesciences)

corazongris:

Inti Illimani - Charagua

(Source: nadianeptura)

(Source: cannabinomad, via moja-moja)

Comfort.

(via moja-moja)

createcreatively:

Vadstena Observance, Medieval Limp Binding, linen cloth cover. 1451-1452, National Library of Sweden.

(via graphandcompass)

nevver:

80s perception of film posters

(via moja-moja)

intergalactic harmony

(Source: neko-nanda, via moja-moja)